GLRA1 anticorps (N-Term)

N° du produit ABIN2017608

Détail du produit anti-GLRA1 anticorps

Antigène: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLRA1 est non-conjugé

Application: Veuillez nous consulter SVP

Specificité: Alpha 1 Glycine Receptor Antibody, pAb, Rabbit detects endogenous levels of mouse alpha 1 Glycine Receptor.

Réactivité croisée: Souris

Réactivité croisée (Details): It is predicted to react with human alpha 1 Glycine Receptor according to sequence homology.
Reactivity to other species is not tested yet.

Attributs du produit: alpha 1 Glycine Receptor Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor (Swiss Prot: P23415).

Purification: Immunoaffinity chromatography

Immunogène: KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor

Isotype: IgG

Information d'application

Commentaires:

Positive Control: Mouse brain

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.

Concentration: 0.5 mg/mL

Buffer: Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.

Détails sur GLRA1

Antigène: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Abstract: GLRA1 Produits

Synonymes: anticorps GLYRA1, anticorps HKPX1, anticorps STHE, anticorps [a]Z1, anticorps B230397M16Rik, anticorps nmf11, anticorps oscillator, anticorps ot, anticorps spasmodic, anticorps spd, anticorps glycine receptor alpha 1, anticorps glycine receptor, alpha 1, anticorps glycine receptor, alpha 1 subunit, anticorps GLRA1, anticorps Glra1, anticorps glra1

Sujet: The glycine receptor is a neurotransmitter-gated ion channel. Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization. The alpha-1 subunit of the glycine receptor is a ligand-gated chloride channel. This inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha and beta subunits. Defects in alpha 1 Glycine Receptor are implicated in the pathophysiology of startle disease (STHE).

Poids moléculaire: Predicted Band Size: 52 KD
Observed Band Size: 48 KD

UniProt: P23415

Pathways: Synaptic Membrane