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FAT4 anticorps (AA 4351-4450) (Biotin)

FAT4 Reactivité: Souris, Rat ELISA, WB, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN2172808
  • Antigène Voir toutes FAT4 Anticorps
    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
    Épitope
    • 14
    • 5
    • 2
    • 1
    AA 4351-4450
    Reactivité
    • 18
    • 14
    • 14
    Souris, Rat
    Hôte
    • 29
    • 3
    Lapin
    Clonalité
    • 29
    • 3
    Polyclonal
    Conjugué
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FAT4 est conjugé à/à la Biotin
    Application
    • 20
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CDHF14
    Isotype
    IgG
    Top Product
    Discover our top product FAT4 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
    Autre désignation
    CDHF14 (FAT4 Produits)
    Synonymes
    anticorps CDHF14, anticorps CDHR11, anticorps FAT-J, anticorps FATJ, anticorps NBLA00548, anticorps 6030410K14Rik, anticorps 9430004M15, anticorps FAT atypical cadherin 4, anticorps FAT4, anticorps Fat4
    Sujet

    Synonyms: Cadherin family member 14, CDHF14, FAT tumor suppressor homolog 4, Fat-like cadherin protein FAT-J, FAT4, FAT4_HUMAN, FATJ, hFat4, Nbla00548, Protocadherin Fat 4.

    Background: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT4 (FAT tumor suppressor homolog 4), also known as FAT-J, CDHF14 or CDHR11, is a 4,981 amino acid single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins and localizes to the primary cilia of kidney. Widely expressed, FAT4 contains thirty-four cadherin domains, six EGF-like domains and two laminin G-like domains. FAT4 may function in the regulation of planar cell polarity.

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