CHI3L1 anticorps (AA 301-383) (Biotin)

N° du produit ABIN2173015

Détail du produit anti-CHI3L1 anticorps (Biotin)

Antigène: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Épitope: AA 301-383

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHI3L1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from Human CHI3L1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CHI3L1

Antigène: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Autre désignation: CHI3L1 (CHI3L1 Produits)

Synonymes: anticorps AW208766, anticorps Brp39, anticorps Gp39, anticorps ASRT7, anticorps CGP-39, anticorps GP-39, anticorps GP39, anticorps HC-gp39, anticorps HCGP-3P, anticorps YKL-40, anticorps YKL40, anticorps YYL-40, anticorps hCGP-39, anticorps GP38K, anticorps CLP-1, anticorps SPC-40, anticorps SPS-40, anticorps Chil1, anticorps BP40, anticorps MGP-40, anticorps chitinase-like 1, anticorps chitinase 3 like 1, anticorps chitinase 3-like 1 (cartilage glycoprotein-39), anticorps Chil1, anticorps CHI3L1, anticorps Chi3l1

Classe de substances: Viral Protein

Sujet:

Synonyms: GP39, ASRT7, GP-39, YKL4, CGP-39, YKL-4, YYL-4, HC-gp39, HCGP-3P, hCGP-39, Chitinase-3-like protein 1, 39 kDa synovial protein, Cartilage glycoprotein 39, CHI3L1

Background: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

ID gène: 1116

UniProt: P36222