Claudin 23 anticorps (AA 25-81) (Biotin)

N° du produit ABIN2173212

Détail du produit anti-Claudin 23 anticorps (Biotin)

Antigène: Claudin 23 (CLDN23)

Épitope: AA 25-81

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 23 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Claudin 23

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Claudin 23

Antigène: Claudin 23 (CLDN23)

Autre désignation: Claudin 23 (CLDN23 Produits)

Synonymes: anticorps CLDN23, anticorps CLDNL, anticorps hCG1646163, anticorps 2310014B08Rik, anticorps claudin 23, anticorps si:ch211-95j8.2, anticorps CLDN23, anticorps si:ch211-95j8.2, anticorps Cldn23

Sujet:

Synonyms: 2310014B08Rik, Claudin23, CLDN 23, CLDN23, CLDNL.

Background: The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-23, also known as CLDN23 or CLDNL, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family. Expressed in stomach and placenta, as well as in germinal center B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space. Human claudin-23 shares 80 % sequence similarity with its mouse counterpart, suggesting a conserved role between species. Overexpression of claudin-23 is associated with colon tumors, implicating claudin-23 as a possible metastasis factor.

Pathways: Cell-Cell Junction Organization, Hepatitis C