FAM48A/P38IP anticorps (AA 21-120) (AbBy Fluor® 647)
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- Antigène Voir toutes FAM48A/P38IP (SUPT20H) Anticorps
- FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
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Épitope
- AA 21-120
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FAM48A/P38IP est conjugé à/à la AbBy Fluor® 647
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human FAM48A
- Isotype
- IgG
- Top Product
- Discover our top product SUPT20H Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
- Autre désignation
- Fam48a (SUPT20H Produits)
- Synonymes
- anticorps SUPT20H, anticorps AA667204, anticorps AI450544, anticorps D3Ertd300e, anticorps Fam48a, anticorps Supt20h, anticorps p38IP, anticorps RGD1307812, anticorps C13, anticorps C13orf19, anticorps FAM48A, anticorps P38IP, anticorps SPT20, anticorps bA421P11.4, anticorps SPT20 homolog, SAGA complex component, anticorps suppressor of Ty 20, anticorps SUPT20H, anticorps Supt20, anticorps Supt20h
- Sujet
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Synonyms: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.
Background: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.
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