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FAM48A/P38IP anticorps (AA 21-120) (Biotin)

SUPT20H Reactivité: Humain ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN2174051
  • Antigène Voir toutes FAM48A/P38IP (SUPT20H) Anticorps
    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
    Épitope
    • 14
    • 2
    • 1
    • 1
    AA 21-120
    Reactivité
    • 19
    • 3
    • 2
    Humain
    Hôte
    • 19
    Lapin
    Clonalité
    • 19
    Polyclonal
    Conjugué
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FAM48A/P38IP est conjugé à/à la Biotin
    Application
    • 13
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Cow
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FAM48A
    Isotype
    IgG
    Top Product
    Discover our top product SUPT20H Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
    Autre désignation
    FAM48A (SUPT20H Produits)
    Synonymes
    anticorps SUPT20H, anticorps AA667204, anticorps AI450544, anticorps D3Ertd300e, anticorps Fam48a, anticorps Supt20h, anticorps p38IP, anticorps RGD1307812, anticorps C13, anticorps C13orf19, anticorps FAM48A, anticorps P38IP, anticorps SPT20, anticorps bA421P11.4, anticorps SPT20 homolog, SAGA complex component, anticorps suppressor of Ty 20, anticorps SUPT20H, anticorps Supt20, anticorps Supt20h
    Sujet

    Synonyms: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

    Background: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

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