FAM48A/P38IP anticorps (AA 21-120) (Biotin)

N° du produit ABIN2174051

Détail du produit anti-FAM48A/P38IP anticorps (Biotin)

Antigène: FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))

Épitope: AA 21-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM48A/P38IP est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FAM48A

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FAM48A/P38IP

Antigène: FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))

Autre désignation: FAM48A (SUPT20H Produits)

Synonymes: anticorps SUPT20H, anticorps AA667204, anticorps AI450544, anticorps D3Ertd300e, anticorps Fam48a, anticorps Supt20h, anticorps p38IP, anticorps RGD1307812, anticorps C13, anticorps C13orf19, anticorps FAM48A, anticorps P38IP, anticorps SPT20, anticorps bA421P11.4, anticorps SPT20 homolog, SAGA complex component, anticorps suppressor of Ty 20, anticorps SUPT20H, anticorps Supt20, anticorps Supt20h

Sujet:

Synonyms: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

Background: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.