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PCDHB6 anticorps (AA 21-120) (Cy3)

PCDHB6 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Cy3
N° du produit ABIN2178286
  • Antigène Tous les produits PCDHB6
    PCDHB6 (Protocadherin beta 6 (PCDHB6))
    Épitope
    • 14
    • 1
    • 1
    AA 21-120
    Reactivité
    Humain
    Hôte
    • 14
    • 3
    Lapin
    Clonalité
    • 15
    • 2
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PCDHB6 est conjugé à/à la Cy3
    Application
    • 12
    • 12
    • 5
    • 3
    • 3
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PCDHB6
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PCDHB6 (Protocadherin beta 6 (PCDHB6))
    Autre désignation
    Pcdhb6 (PCDHB6 Produits)
    Synonymes
    anticorps PCDH-BETA6, anticorps Pcdhb5B, anticorps PcdhbF, anticorps protocadherin beta 6, anticorps PCDHB6, anticorps Pcdhb6
    Sujet

    Synonyms: PCDH beta6,,PCDH beta 6, PCDHB 6, Protocadherin beta 6.

    Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.

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