SHROOM1 anticorps (AA 121-220) (Biotin)

N° du produit ABIN2179203

Détail du produit anti-SHROOM1 anticorps (Biotin)

Antigène: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Épitope: AA 121-220

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHROOM1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SHROOM1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SHROOM1

Antigène: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Autre désignation: SHROOM1 (SHROOM1 Produits)

Synonymes: anticorps apx, anticorps APXL2, anticorps 1300007L22Rik, anticorps Apx, anticorps Shrm1, anticorps RGD1308066, anticorps shrm, anticorps shroom family member 1, anticorps shroom family member 1 L homeolog, anticorps SHROOM1, anticorps shroom1, anticorps Shroom1, anticorps shroom1.L

Sujet:

Synonyms: Apical protein 2, APXL2, Protein Shroom1, SHRM1_HUMAN, Shroom family member 1, Shroom1.

Background: SHROOM1 is an 852 amino acid protein that contains one ASD1 domain and one ASD2 domain. Localized to both the cytoplasm and the cytoskeleton, SHROOM1 interacts with Actin and is thought to be involved in microtubule assembly during cell elongation, possibly playing a role in the development of the nervous system. Multiple isoforms of SHROOM1 exist due to alternative splicing events. The gene encoding SHROOM1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.