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TAB3 anticorps (PE)

TAB3 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal PE
N° du produit ABIN2179514
  • Antigène Voir toutes TAB3 Anticorps
    TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
    Reactivité
    • 40
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 39
    • 1
    Lapin
    Clonalité
    • 39
    • 1
    Polyclonal
    Conjugué
    • 19
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TAB3 est conjugé à/à la PE
    Application
    • 24
    • 21
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TAB3
    Isotype
    IgG
    Top Product
    Discover our top product TAB3 Anticorps primaire
  • Indications d'application
    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Antigène
    TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
    Autre désignation
    Tab3 (TAB3 Produits)
    Synonymes
    anticorps MAP3K7IP3, anticorps NAP1, anticorps 4921526G09Rik, anticorps Map3k7ip3, anticorps mKIAA4135, anticorps map3k7ip3, anticorps nap1, anticorps tab3, anticorps tab3-a, anticorps tab3-b, anticorps map3k7ip3l, anticorps si:ch211-232d19.8, anticorps si:dkey-30h22.6, anticorps TGF-beta activated kinase 1 and MAP3K7 binding protein 3, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 3, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog, anticorps TAB3, anticorps Tab3, anticorps tab3.S, anticorps tab3
    Sujet

    Synonyms: MAP3K7IP 3, Mitogen activated protein kinase kinase kinase 7 interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF kappa B activating protein 1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, TAB3, TAB3_HUMAN, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1-binding protein 3.

    Background: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

    ID gène
    257397
    UniProt
    Q8N5C8
    Pathways
    Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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