FERMT3 anticorps (AA 401-500) (Biotin)

N° du produit ABIN2179987

Détail du produit anti-FERMT3 anticorps (Biotin)

Antigène: FERMT3 (Fermitin Family Member 3 (FERMT3))

Épitope: AA 401-500

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FERMT3 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human URP2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FERMT3

Antigène: FERMT3 (Fermitin Family Member 3 (FERMT3))

Autre désignation: URP2 (FERMT3 Produits)

Synonymes: anticorps C79673, anticorps Kindlin3, anticorps RGD1310168, anticorps MGC69069, anticorps MGC88900, anticorps KIND3, anticorps MIG-2, anticorps MIG2B, anticorps UNC112C, anticorps URP2, anticorps URP2SF, anticorps zgc:64101, anticorps fermitin family member 3, anticorps fermitin family member 3 L homeolog, anticorps fermitin family member 3b, anticorps Fermt3, anticorps fermt3.L, anticorps fermt3, anticorps FERMT3, anticorps fermt3b

Sujet:

Synonyms: Fermitin family homolog 3, Fermitin family member 3, FERMT3, Kind3, Kindlin 3, Kindlin-3, Kindlin3, MGC10966, MIG 2, MIG2 like protein, MIG2-like protein, MIG2B, Unc 112 related protein 2, Unc-112-related protein 2, UNC112C, URP2_HUMAN, URP2SF.

Background: Kindlin-3 is a 667 amino acid protein that localizes to both the cell membrane and the cytoplasm and contains one PH domain and one FERM domain. Expressed at high levels in lymph node tissue and at lower levels in spleen, thymus, stomach, placenta, lung, testis and small intestine, Kindlin-3 is thought to be involved in cell adhesion events and may play a role in apoptosis. Kindlin-3 is overexpressed in B-cell malignancies, suggesting that, via its ability to affect cell adhesion, Kindlin-3 may participate in tumor transformation and metastasis. Two isforms of Kindlin-3, designated short and long, exist due to alternative splicing events.