Vinexin anticorps (AA 401-500) (AbBy Fluor® 488)
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- Antigène Voir toutes Vinexin (Sorbs3) Anticorps
- Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))
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Épitope
- AA 401-500
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Vinexin est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Vinexin
- Isotype
- IgG
- Top Product
- Discover our top product Sorbs3 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))
- Autre désignation
- Vinexin (Sorbs3 Produits)
- Synonymes
- anticorps zgc:113031, anticorps si:dkey-162f21.1, anticorps SCAM-1, anticorps SH3P3, anticorps Sh3d4, anticorps vinexin-g, anticorps SCAM1, anticorps SH3D4, anticorps sorbin and SH3 domain containing 3, anticorps SORBS3, anticorps sorbs3, anticorps Sorbs3
- Sujet
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Synonyms: SCAM 1, SCAM1, SH3 containing adapter molecule 1, SH3 domain containing adapter molecule 1, SH3D4, Sorbin and SH3 domain containing 3, Sorbin and SH3 domain containing protein 3, Sorbs3, Vinexin alpha, Vinexin, Vinexin beta (SH3 containing adaptor molecule 1).
Background: Vinexin is a 671 amino acid protein that is expressed as two isoforms, designated Vinexin alpha and Vinexin beta. Localized to cell junctions in both the cytoplasm and the cytoskeleton, Vinexin alpha functions to promote Actin stress fiber formation, playing an important role in modification of the Actin cytoskeleton. Like Vinexin alpha, Vinexin beta is localized to cell junctions in the cytoplasm, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation. Although Vinexin alpha and Vinexin beta have different roles within the cell, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, including placenta, heart, liver, brain, pancreas and skeletal muscle. Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, signal transduction and cytoskeletal organization throughout the cell.
- Pathways
- Signalisation MAPK
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