LY86 anticorps

N° du produit ABIN2191781

Détail du produit anti-LY86 anticorps

Antigène: LY86 (Lymphocyte Antigen 86 (LY86))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp LY86 est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Stérilité: 0.2 μm filtered

Clone: MD113

Information d'application

Indications d'application: For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Références pour anticorps anti-LY86 (ABIN2191781)

Nagai, Shimazu, Ogata, Akashi, Sudo, Yamasaki, Hayashi, Iwakura, Kimoto, Miyake: "Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide." dans: Blood, Vol. 99, Issue 5, pp. 1699-705, (2002) (PubMed).

Détails sur LY86

Antigène: LY86 (Lymphocyte Antigen 86 (LY86))

Autre désignation: Md-1 (LY86 Produits)

Synonymes: anticorps MD-1, anticorps MMD-1, anticorps dJ80N2.1, anticorps MD1, anticorps LY86, anticorps lymphocyte antigen 86, anticorps LY86, anticorps Ly86

Sujet: The monoclonal antibody MD113 reacts with mouse MD-1. MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS. The MD113 antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.

Pathways: Toll-Like Receptors Cascades