CXCL10 anticorps

N° du produit ABIN2191895

Détail du produit anti-CXCL10 anticorps

Antigène: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCL10 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)

Stérilité: 0.2 μm filtered

Clone: 6D4

Information d'application

Indications d'application: For immunohistochemistry, flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Positive Acitvated plasmacytoid dendritic cells control Negative Normal liver control 1

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

Références pour anticorps anti-CXCL10 (ABIN2191895)

Curbishley, Eksteen, Gladue, Lalor, Adams: "CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow." dans: The American journal of pathology, Vol. 167, Issue 3, pp. 887-99, (2005) (PubMed).

Giustizieri, Albanesi, Scarponi, De Pità, Girolomoni: "Nitric oxide donors suppress chemokine production by keratinocytes in vitro and in vivo." dans: The American journal of pathology, Vol. 161, Issue 4, pp. 1409-18, (2002) (PubMed).

Hamamdzic, Phillips-Dorsett, Altman-Hamamdzic, London, London: "Reovirus triggers cell type-specific proinflammatory responses dependent on the autocrine action of IFN-beta." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 280, Issue 1, pp. L18-29, (2001) (PubMed).

Détails sur CXCL10

Antigène: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Autre désignation: C-X-C Motif Chemokine 10 (CXCL10 Produits)

Synonymes: anticorps CXCL10, anticorps C7, anticorps IFI10, anticorps INP10, anticorps IP-10, anticorps SCYB10, anticorps crg-2, anticorps gIP-10, anticorps mob-1, anticorps CRG-2, anticorps IP10, anticorps Ifi10, anticorps Scyb10, anticorps C-X-C motif chemokine ligand 10, anticorps C-X-C motif chemokine 10, anticorps chemokine (C-X-C motif) ligand 10, anticorps CXCL10, anticorps cxl10, anticorps Cxcl10

Sujet: The monoclonal antibody 6D4 recognizes human C-X-C motif chemokine 10 (IP-10), a protein of 98 amino acids. IP-10, also known as CXCL10, functions as ligand for the CXCR3 receptor. IP-10 belongs to the α-chemokine (C-X-C) family, which can be divided in two subfamilies: (1) potent chemoattractants for neutrophils, like IL-8 and (2) potent chemoattractants for lymphocytes, like the IFNγ inducible protein (IP)-10. IP-10 is produced by a wide variety of cell types ranging from neutrophils, dendritic cells and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis, psoriasis and acute anterior uveitis. Various observations strongly suggest a role for the C-X-C chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Furthermore IP-10 is associated with acute rejection processes estimated by the predictive properties of urinary IP-10 expression for the short- and long-term graft function after kidney transplantation. Aliases 10 kDa interferon gamma-induced protein, CXCL10, Small-inducible cytokine B10 Immunogen Recombinant human IP-10