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RAB11FIP3 anticorps (C-Term)

RAB11FIP3 Reactivité: Souris ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN233825
  • Antigène Voir toutes RAB11FIP3 Anticorps
    RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II) (RAB11FIP3))
    Épitope
    • 4
    • 1
    • 1
    C-Term
    Reactivité
    • 14
    • 4
    • 4
    Souris
    Hôte
    • 13
    • 1
    Lapin
    Clonalité
    • 13
    • 1
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RAB11FIP3 est non-conjugé
    Application
    • 5
    • 4
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Attributs du produit
    Concentration Definition: by UV absorbance at 280 nm
    Immunogène
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids spanning the one-third of human FIP3.
    Immunogentype:Recombinant
    Isotype
    IgG
    Top Product
    Discover our top product RAB11FIP3 Anticorps primaire
  • Indications d'application
    This affinity purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Although the predicted molecular weight of FIP3 is 82.4 kDa, a band corresponding to FIP3 was observed at 120 kDa in human cell lysates and at 150 kDa in mouse cell lysates.  The identity of a 40 kDa band, observed in western blotting against both HeLa and 293T cell lysates, is unknown (personal communication, P. Randazzo, CCR-NCI, Bethesda, MD).
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.19 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II) (RAB11FIP3))
    Abstract
    RAB11FIP3 Produits
    Synonymes
    anticorps LRRGT00043, anticorps RGD1308952, anticorps MNDPK, anticorps RAB11FIP3, anticorps CART1, anticorps Rab11-FIP3, anticorps Cart1, anticorps D030060O14Rik, anticorps mKIAA0665, anticorps si:ch211-153c20.4, anticorps zC153C20.4, anticorps RAB11 family interacting protein 3, anticorps NME/NM23 nucleoside diphosphate kinase 4, anticorps RAB11 family interacting protein 3 (class II), anticorps Rab11fip3, anticorps NME4, anticorps RAB11FIP3, anticorps rab11fip3
    Sujet
    Rab11 Family-Interacting Protein 3 (FIP3)/Arfophilin-1 and FIP4/Arfophilin-2 are dual effectors for Rab11 and the ADP-ribosylation factor Arf6.  Rab11 and Arf6 are involved in membrane delivery from recycling endosomes to the plasma membrane during cytokinesis.  The dual Rab11/Arf6 binding proteins, FIP3 and FIP4, function in the delivery of recycling endosomes to the cleavage furrow and are, together with Rab11, essential for completion of abscission, the terminal step of cytokinesis.  An interaction between Rab11-FIP3 and ASAP1 has also been identified (personal communication, P. Randazzo, CCR-NCI, Bethesda, MD).  ASAP1 is an Arf GTPase-activating protein that has been implicated in the invasive properties of uveal melanoma and mammary carcinoma.
    Synonyms: IkB kinase associated protein 1 antibody, IkB kinase subunit gamma antibody, Inhibitor of nuclear factor kappa B kinase subunit gamma antibody, AMCBX1 antibody, FIP 3 antibody
    ID gène
    9727, 7662234
    UniProt
    O75154
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