RAB11FIP3 anticorps (C-Term)

N° du produit ABIN233825

Détail du produit anti-RAB11FIP3 anticorps

Antigène: RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II) (RAB11FIP3))

Épitope: C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB11FIP3 est non-conjugé

Application: ELISA, Western Blotting (WB)

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids spanning the one-third of human FIP3.
Immunogentype:Recombinant

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Although the predicted molecular weight of FIP3 is 82.4 kDa, a band corresponding to FIP3 was observed at 120 kDa in human cell lysates and at 150 kDa in mouse cell lysates.  The identity of a 40 kDa band, observed in western blotting against both HeLa and 293T cell lysates, is unknown (personal communication, P. Randazzo, CCR-NCI, Bethesda, MD).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.19 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur RAB11FIP3

Antigène: RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II) (RAB11FIP3))

Abstract: RAB11FIP3 Produits

Synonymes: anticorps LRRGT00043, anticorps RGD1308952, anticorps MNDPK, anticorps RAB11FIP3, anticorps CART1, anticorps Rab11-FIP3, anticorps Cart1, anticorps D030060O14Rik, anticorps mKIAA0665, anticorps si:ch211-153c20.4, anticorps zC153C20.4, anticorps RAB11 family interacting protein 3, anticorps NME/NM23 nucleoside diphosphate kinase 4, anticorps RAB11 family interacting protein 3 (class II), anticorps Rab11fip3, anticorps NME4, anticorps RAB11FIP3, anticorps rab11fip3

Sujet: Rab11 Family-Interacting Protein 3 (FIP3)/Arfophilin-1 and FIP4/Arfophilin-2 are dual effectors for Rab11 and the ADP-ribosylation factor Arf6.  Rab11 and Arf6 are involved in membrane delivery from recycling endosomes to the plasma membrane during cytokinesis.  The dual Rab11/Arf6 binding proteins, FIP3 and FIP4, function in the delivery of recycling endosomes to the cleavage furrow and are, together with Rab11, essential for completion of abscission, the terminal step of cytokinesis.  An interaction between Rab11-FIP3 and ASAP1 has also been identified (personal communication, P. Randazzo, CCR-NCI, Bethesda, MD).  ASAP1 is an Arf GTPase-activating protein that has been implicated in the invasive properties of uveal melanoma and mammary carcinoma.
Synonyms: IkB kinase associated protein 1 antibody, IkB kinase subunit gamma antibody, Inhibitor of nuclear factor kappa B kinase subunit gamma antibody, AMCBX1 antibody, FIP 3 antibody

ID gène: 9727, 7662234

UniProt: O75154