CDKN2AIP anticorps
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- Antigène Voir toutes CDKN2AIP Anticorps
- CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDKN2AIP est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human CDKN2AIP
- Isotype
- IgG
- Top Product
- Discover our top product CDKN2AIP Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Conseil sur la manipulation
- Avoid freeze / thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))
- Autre désignation
- CDKN2AIP (CDKN2AIP Produits)
- Synonymes
- anticorps CARF, anticorps 4921511I16Rik, anticorps AW208986, anticorps CDKN2AIP, anticorps RGD1305302, anticorps CDKN2A interacting protein, anticorps CDKN2A interacting protein L homeolog, anticorps CDKN2AIP, anticorps Cdkn2aip, anticorps cdkn2aip, anticorps cdkn2aip.L
- Sujet
- CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
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