TLR3 anticorps
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- Antigène Voir toutes TLR3 Anticorps
- TLR3 (Toll-Like Receptor 3 (TLR3))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TLR3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human TLR3
- Isotype
- IgG
- Top Product
- Discover our top product TLR3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Conseil sur la manipulation
- Avoid freeze / thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Autre désignation
- TLR3 (TLR3 Produits)
- Synonymes
- anticorps CD283, anticorps IIAE2, anticorps AI957183, anticorps zgc:123006, anticorps toll like receptor 3, anticorps toll-like receptor 3, anticorps TLR3, anticorps Tlr3, anticorps tlr3
- Sujet
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
- Poids moléculaire
- Calculated MW: 104 kDa
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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