Aconitase 1 anticorps
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- Antigène Voir toutes Aconitase 1 (ACO1) Anticorps
- Aconitase 1 (ACO1)
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Aconitase 1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Affinity purification
- Immunogène
- Synthetic peptide of human ACO1
- Isotype
- IgG
- Top Product
- Discover our top product ACO1 Anticorps primaire
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- Indications d'application
- WB 1:1000-1:5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Conseil sur la manipulation
- Avoid freeze / thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Aconitase 1 (ACO1)
- Autre désignation
- ACO1 (ACO1 Produits)
- Synonymes
- anticorps ACONS, anticorps IREB1, anticorps IREBP, anticorps IREBP1, anticorps IRP1, anticorps Acon1, anticorps Ratireb, anticorps ratireb, anticorps Aco1, anticorps AI256519, anticorps Aco-1, anticorps Irebp, anticorps Irp1, anticorps aconitase 1, anticorps aconitase 1, soluble, anticorps aconitase 1 L homeolog, anticorps ACO1, anticorps Aco1, anticorps aco1.L
- Sujet
- Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
- Poids moléculaire
- Calculated MW: 98 kDa
- NCBI Accession
- NP_002188
- Pathways
- Transition Metal Ion Homeostasis
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