DIO2 anticorps
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- Antigène Voir toutes DIO2 Anticorps
- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DIO2 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Synthetic peptide of human DIO2
- Isotype
- IgG
- Top Product
- Discover our top product DIO2 Anticorps primaire
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- Indications d'application
- IHC 1:25-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Conseil sur la manipulation
- Avoid freeze / thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
- Autre désignation
- DIO2 (DIO2 Produits)
- Synonymes
- anticorps 5DII, anticorps D2, anticorps DIOII, anticorps SelY, anticorps TXDI2, anticorps AI324267, anticorps Deio2, anticorps cb684, anticorps DIO2, anticorps dio2-A, anticorps 5dii, anticorps sely, anticorps txdi2, anticorps iodothyronine deiodinase 2, anticorps deiodinase, iodothyronine, type II, anticorps deiodinase, iodothyronine, type 2 L homeolog, anticorps deiodinase, iodothyronine, type 2, anticorps type II iodothyronine deiodinase, anticorps DIO2, anticorps Dio2, anticorps dio2, anticorps dio2.L, anticorps LOC100861220
- Sujet
- The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
- NCBI Accession
- NP_000784
- Pathways
- Hormone Transport, Hormone Activity
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