CBX1 anticorps (AA 176-185)

N° du produit ABIN2452034

Détail du produit anti-CBX1 anticorps

Antigène: CBX1 (Chromobox Homolog 1 (CBX1))

Épitope: AA 176-185

Reactivité: Humain, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq)

Réactivité croisée (Details): Expected to react with mouse, chicken, zebra fish, Xenopus, Drosophila orthologs due to the sequence identity of the immunogen.

Attributs du produit: The product is prepared by immunizing rabbit with the synthetic peptide CNEDDDKKDDKN including the C-terminal sequence (176-185) of human HP1beta and purified by affinity purification with the peptide. The antiserum was prepared by the direction of Prof. T. Haraguchi.

Purification: Affinity purified

Stérilité: Sterile filtered

Isotype: IgG

Information d'application

Indications d'application: 1) Western blotting: 1/2,000~1/10,000
2) Immunofluorescence staining
3) Chromatin immunoprecipitation (ChIP)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.44 mg/mL

Buffer: 0.12 M sodium phosphate buffer ( pH 7.4), 50 % glycerol

Agent conservateur: Azide free

Stock: -20 °C/-80 °C

Stockage commentaire: -20 C (For long term storage: -70 C)

Références pour anticorps anti-CBX1 (ABIN2452034)

Lomberk, Wallrath, Urrutia: "The Heterochromatin Protein 1 family." dans: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).

Wang, Koyama, Nishida, Haraguchi, Reith, Tsukamoto: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." dans: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).

Kametaka, Takagi, Hayakawa, Haraguchi, Hiraoka, Yoneda: "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 7, Issue 12, pp. 1231-42, (2002) (PubMed).

Détails sur CBX1

Antigène: CBX1 (Chromobox Homolog 1 (CBX1))

Autre désignation: HP1 beta/cbx1 (CBX1 Produits)

Synonymes: anticorps CBX, anticorps HP1-BETA, anticorps HP1Hs-beta, anticorps HP1Hsbeta, anticorps M31, anticorps MOD1, anticorps p25beta, anticorps Cbx, anticorps Cbx-rs2, anticorps E430007M08Rik, anticorps HP1B, anticorps Hp1beta, anticorps cbx1, anticorps wu:fe14b09, anticorps zgc:55739, anticorps zgc:86924, anticorps chromobox 1, anticorps chromobox homolog 1a (HP1 beta homolog Drosophila), anticorps chromobox 1 S homeolog, anticorps chromobox homolog 1b (HP1 beta homolog Drosophila), anticorps CBX1, anticorps Cbx1, anticorps cbx1a, anticorps cbx1.S, anticorps cbx1b

Sujet: Heterochromatin protein 1 (HP1) is a major component of heterochromatin which plays a role in assembly of various proteins on chromatin and gene silencing. The HP1 family is evolutionally conserved, with members in fungi, plants and animals but not prokaryotes, and there are multiple members within the same species. The HP1 family proteins are encoded by a class of genes known as the chromobox (CBX) genes. In humans, HP1beta is encoded by the Chromobox homolog 1 (CBX1) gene located on chromosome 17q21.32. HP1beta has been observed to interact directly or indirectly with several non-histone proteins with a wide variety of functions.

UniProt: P83916