NUP153 anticorps (AA 610-1191)

N° du produit ABIN2452062

Détail du produit anti-NUP153 anticorps

Antigène: NUP153 (Nucleoporin 153kDa (NUP153))

Épitope: AA 610-1191

Reactivité: Rat

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp NUP153 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Specific to human, mouse, rat and monkey Nup153 proteins.

Réactivité croisée (Details): Not tested for other species

Attributs du produit: When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.

Purification: Purified

Stérilité: Sterile filtered

Immunogène: Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)

Clone: R4C8

Isotype: IgG2a kappa

Information d'application

Indications d'application: 1. Western blotting: 160 kDa single band in Hela cell extract
2. Immunocytochemistry
3. ELISA
Other applications have not been tested.

Additional comments:
When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
R4C8 works in immuno-cytochemistry very well.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Upon receipt aliquot and store at -20 C

Références pour anticorps anti-NUP153 (ABIN2452062)

Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: "Nanomechanical basis of selective gating by the nuclear pore complex." dans: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).

Ullman, Shah, Powers, Forbes: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." dans: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, (1999) (PubMed).

Détails sur NUP153

Antigène: NUP153 (Nucleoporin 153kDa (NUP153))

Autre désignation: Nup153 (NUP153 Produits)

Synonymes: anticorps CG4453, anticorps Dmel\\CG4453, anticorps NUP153, anticorps Nup 153, anticorps dNup153, anticorps dmNup153, anticorps nup153, anticorps NUCZINK, anticorps B130015D15Rik, anticorps C88147, anticorps HNUP153, anticorps N153, anticorps Nucleoporin 153kD, anticorps nucleoporin 153, anticorps nucleoporin 153kDa L homeolog, anticorps Nup153, anticorps NUP153, anticorps nup153.L

Sujet: The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.

UniProt: P49790

Pathways: Protein targeting to Nucleus