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NUP98 anticorps (AA 1-466)

NUP98 Reactivité: Humain, Souris, Rat, Saccharomyces cerevisiae, Schizosaccharomyces pombe WB, ELISA, IF, ICC, DB Hôte: Rat Monoclonal 2H10 unconjugated
N° du produit ABIN2452066
  • Antigène Voir toutes NUP98 Anticorps
    NUP98 (Nucleoporin 98kDa (NUP98))
    Épitope
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-466
    Reactivité
    • 47
    • 16
    • 13
    • 8
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Saccharomyces cerevisiae, Schizosaccharomyces pombe
    Hôte
    • 36
    • 12
    Rat
    Clonalité
    • 35
    • 13
    Monoclonal
    Conjugué
    • 38
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NUP98 est non-conjugé
    Application
    • 35
    • 14
    • 13
    • 9
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)
    Réactivité croisée (Details)
    This antibody does not react with Tetrahymena.
    Other species have not been tested.
    Purification
    Purified
    Stérilité
    Sterile filtered
    Immunogène
    Recombinant GST-fused human Nup98 (aa 1-466)
    Clone
    2H10
    Isotype
    IgG2c kappa
  • Indications d'application
    1) Western blotting
    2) Immunocytochemistry
    3) ELISA
    4) Dot blotting

    Properties:
    When injected into the cytoplasm, this antibody accumulates into the nuclear pores of HeLa cells and inhibits nuclear localization of endogenous Ran.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol. Azide- and carrier protein-free.
    Agent conservateur
    Azide free
    Stock
    -20 °C
    Stockage commentaire
    Upon arrival centrifuge briefly and store at -20 C.
  • Iwamoto, Asakawa, Ohtsuki, Osakada, Koujin, Hiraoka, Haraguchi: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." dans: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).

    Fukuhara, Ozaki, Shikata, Katahira, Yoneda, Ogino, Tachibana: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." dans: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).

  • Antigène
    NUP98 (Nucleoporin 98kDa (NUP98))
    Autre désignation
    Nup98 (NUP98 Produits)
    Synonymes
    anticorps CG10198, anticorps CG10201, anticorps Dmel\\CG10198, anticorps Nup 96, anticorps Nup 98, anticorps Nup-98, anticorps Nup96, anticorps Nup98, anticorps Nup98-Nup96, anticorps Nup98/96, anticorps l(3)95BCd, anticorps nup145, anticorps nup98-96, anticorps GB12688, anticorps NUP98, anticorps 4732457F17, anticorps AI849286, anticorps im:7151238, anticorps zgc:113968, anticorps zgc:63593, anticorps ADIR2, anticorps NUP196, anticorps NUP96, anticorps Nucleoporin 98-96kD, anticorps nuclear pore complex protein Nup98-Nup96, anticorps nucleoporin 98, anticorps nucleoporin 98kDa, anticorps nucleoporin 98 L homeolog, anticorps Nup98-96, anticorps LOC408335, anticorps NUP98, anticorps LOC587580, anticorps Nup98, anticorps nup98, anticorps nup98.L
    Sujet
    Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 plays a specific role in the RNA export. Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. This hybridoma has been established by Prof. T. Tachibana's Lab. at Osaka City Univ.
    UniProt
    Q9HDC8
    Pathways
    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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