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RAD18 anticorps (C-Term)

RAD18 Reactivité: Humain WB, ELISA, IF, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2452086
  • Antigène Voir toutes RAD18 Anticorps
    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
    Épitope
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 50
    • 26
    • 22
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 7
    Lapin
    Clonalité
    • 37
    • 13
    Polyclonal
    Conjugué
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp RAD18 est non-conjugé
    Application
    • 28
    • 16
    • 8
    • 8
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Réactivité croisée (Details)
    Not reactive to mouse Rad18
    Purification
    Affinity purified with His-tagged Rad18 protein affinity column
    Immunogène
    GST-fusion protein containing 113 carboxyl terminal of human Rad18
    Isotype
    IgG
    Top Product
    Discover our top product RAD18 Anticorps primaire
  • Indications d'application
    1) Western blotting: 1,000 fold dilution
    2) Indirect immunofluorescence staining
    3) Immunoprecipitation
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Agent conservateur
    Azide free
    Stock
    -20 °C
  • Watanabe, Tateishi, Kawasuji, Tsurimoto, Inoue, Yamaizumi: "Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination." dans: The EMBO journal, Vol. 23, Issue 19, pp. 3886-96, (2004) (PubMed).

    Miyase, Tateishi, Watanabe, Tomita, Suzuki, Inoue, Yamaizumi: "Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination." dans: The Journal of biological chemistry, Vol. 280, Issue 1, pp. 515-24, (2004) (PubMed).

    Tateishi, Sakuraba, Masuyama, Inoue, Yamaizumi: "Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 14, pp. 7927-32, (2000) (PubMed).

  • Antigène
    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
    Autre désignation
    Rad18 (RAD18 Produits)
    Synonymes
    anticorps RNF73, anticorps 2810024C04Rik, anticorps Rad18sc, anticorps zgc:55577, anticorps RAD18, anticorps DDBDRAFT_0218120, anticorps DDBDRAFT_0304878, anticorps DDB_0218120, anticorps DDB_0304878, anticorps DKFZp469H0810, anticorps RAD18, E3 ubiquitin protein ligase, anticorps RAD18 E3 ubiquitin protein ligase, anticorps E3 ubiquitin-protein ligase RAD18, anticorps E3 ubiquitin-protein ligase, anticorps DNA repair protein and ATPase, anticorps C3HC4-type zinc finger-containing protein, anticorps RAD18, anticorps Rad18, anticorps rad18
    Sujet
    The Rad6-Rad18 pair of genes plays a critical role in post-replication repair of damaged DNA. Rad6 protein functions as an E2 enzyme and Rad18 (495 aa, 56 kDa) as an ubiquitine ligase (E3) which ubiquitinates PCNA. Rad18 recruits translesion DNA polymerases to damaged DNA.
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