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SARS-CoV Spike anticorps

SARS-CoV S Reactivité: SARS Coronavirus (SARS-CoV) ELISA, WB, IF, IC Hôte: Souris Monoclonal 3A2 unconjugated
N° du produit ABIN2452119
  • Antigène Voir toutes SARS-CoV Spike (SARS-CoV S) Anticorps
    SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))
    Reactivité
    • 40
    • 16
    SARS Coronavirus (SARS-CoV)
    Hôte
    • 38
    • 2
    Souris
    Clonalité
    • 38
    • 2
    Monoclonal
    Conjugué
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SARS-CoV Spike est non-conjugé
    Application
    • 25
    • 17
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunochromatography (IC)
    Attributs du produit
    Monoclonal antibody 3A2 recognizes the spike protein consisting of 1181 amino acids, which migrates at 200 kDa position on SDS-PAGE due to its glyco-chains.
    Purification
    Purified
    Stérilité
    Sterile filtered
    Clone
    3A2
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product SARS-CoV S Anticorps primaire
  • Indications d'application
    1) Western blotting: 0. 1~0. 3 g/mL
    2) Immunofluoresece staining (IHC)
    3) ELISA Isoform: IgG2b (kappa)
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Agent conservateur
    Azide free
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    -20 C (For long term storage: -80 C)
  • Jin, Nesbitt, Yang, Chen, Horowitz, Jones, Vandergaast, Carey, Reiter, Russell, Kyratsous, Hooper, Hamilton, Ferreira, Deng, Straus, Baras, Hillyer, Luchsinger: "Seroprevalence of anti-SARS-CoV-2 antibodies in a cohort of New York City metro blood donors using multiple SARS-CoV-2 serological assays: Implications for controlling the epidemic and "Reopening"." dans: PloS one, Vol. 16, Issue 4, pp. e0250319, (2021) (PubMed).

    Nesbitt, Jin, Hogan, Yang, Chen, Chan, Simon, Vargas, King, Huard, Bandy, Hillyer, Luchsinger: "Low Seroprevalence of SARS-CoV-2 in Rhode Island blood donors during may 2020 as determined using multiple serological assay formats." dans: BMC infectious diseases, Vol. 21, Issue 1, pp. 871, (2021) (PubMed).

    Luchsinger, Ransegnola, Jin, Muecksch, Weisblum, Bao, George, Rodriguez, Tricoche, Schmidt, Gao, Jawahar, Pal, Schnall, Zhang, Strauss, Yazdanbakhsh, Hillyer, Bieniasz, Hatziioannou: "Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID19 Patients." dans: Journal of clinical microbiology, (2020) (PubMed).

    Satija, Lal: "The molecular biology of SARS coronavirus." dans: Annals of the New York Academy of Sciences, Vol. 1102, pp. 26-38, (2007) (PubMed).

    Yamate, Yamashita, Goto, Tsuji, Li, Warachit, Yunoki, Ikuta: "Establishment of Vero E6 cell clones persistently infected with severe acute respiratory syndrome coronavirus." dans: Microbes and infection / Institut Pasteur, Vol. 7, Issue 15, pp. 1530-40, (2005) (PubMed).

  • Antigène
    SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))
    Autre désignation
    SARS-CoV Spike (SARS-CoV S Produits)
    Classe de substances
    Viral Protein
    Sujet
    A novel type of coronavirus has been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Spike glycoprotein is essential for the infection and directly binds to the virus receptor, ACE2 (Angiotensin-Converting Enzyme 2). Hybridoma 3A2 has been isolated by injecting mouse with SARS virus and as the clone which produces antibody that specifically reacts with the virus-infected cell, in the laboratory of Prof. K. Ikuta of Osaka University.
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