CD248 anticorps (full length)

N° du produit ABIN2452152

Détail du produit anti-CD248 anticorps

Antigène: CD248 (CD248 Molecule, Endosialin (CD248))

Épitope: full length

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD248 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Attributs du produit: Rabbit polyclonal antibody affinity purified with the immunogen after adsorption of anti-GST antibody with GST-affinity column.

Purification: Affinity purified

Immunogène: GST-full length Tem1 fusion protein expressed in E. coli

Isotype: IgG

Information d'application

Indications d'application: 1) Western blotting: 1/250~1/500
2) Immunoprecipitation

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 1 mg/mL BSA as carrier, 0.09 % sodium azide, 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CD248

Antigène: CD248 (CD248 Molecule, Endosialin (CD248))

Autre désignation: Tem1 (CD248 Produits)

Synonymes: anticorps CD164L1, anticorps TEM1, anticorps 2610111G01Rik, anticorps AI842296, anticorps Cd164l1, anticorps Tem1, anticorps fb96b12, anticorps wu:fb96b12, anticorps zgc:162651, anticorps CD248 molecule, anticorps CD248 antigen, endosialin, anticorps CD248 molecule, endosialin a, anticorps CD248, anticorps Cd248, anticorps cd248a

Sujet: Background: Tem1 is a low-molecular-weight GTP-binding protein (GTPase) which is required for the termination of M phase in cell division. The defect of Tem1 was lethal, and the Tem1-defective cells were arrested at telophase with high H1-kinase activity, indicating that Tem1 is required to exit from M phase. The defect of Tem1 was suppressed by a high dose of cdc15, which encodes a protein kinase. Tem1 functions upstream of cdc15 kinase and may be required to activate the cdc15 protein kinase pathway. A cascade consisting of Tem1 and kinases act to terminate mitosis.