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PATZ1 anticorps

ZNF278 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2458359
  • Antigène Voir toutes PATZ1 (ZNF278) Anticorps
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    Reactivité
    • 22
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 18
    • 4
    Lapin
    Clonalité
    • 20
    • 2
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PATZ1 est non-conjugé
    Application
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogène
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PATZ1.
    Top Product
    Discover our top product ZNF278 Anticorps primaire
  • Indications d'application
    PATZ1 antibody can be used for detection of PATZ1 by ELISA at 1:1562500. PATZ1 antibody can be used for detection of PATZ1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Conseil sur la manipulation
    As with any antibody avoid repeat freeze-thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PATZ1 antibody at -20 °C.
  • Antigène
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    Autre désignation
    PATZ1 (ZNF278 Produits)
    Synonymes
    anticorps ZNF278, anticorps MAZR, anticorps PATZ, anticorps RIAZ, anticorps ZBTB19, anticorps ZSG, anticorps dJ400N23, anticorps 8430401L15Rik, anticorps AI447519, anticorps Mazr, anticorps Patz, anticorps Zfp278, anticorps Znf278, anticorps POZ/BTB and AT hook containing zinc finger 1, anticorps POZ/BTB and AT hook containing zinc finger 1 S homeolog, anticorps POZ (BTB) and AT hook containing zinc finger 1, anticorps POZ-, AT hook-, and zinc finger-containing protein 1, anticorps PATZ1, anticorps patz1.S, anticorps Patz1, anticorps LOC100153931
    Sujet
    PATZ1 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t (1,22) (p36.1,q12).The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t (1,22) (p36.1,q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.
    Poids moléculaire
    74 kDa
    ID gène
    23598
    NCBI Accession
    NP_055138
    UniProt
    Q9HBE1
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