A1CF anticorps
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- Antigène Voir toutes A1CF Anticorps
- A1CF (APOBEC1 Complementation Factor (A1CF))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp A1CF est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human A1CF.
- Top Product
- Discover our top product A1CF Anticorps primaire
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- Indications d'application
- A1CF antibody can be used for detection of A1CF by ELISA at 1:1562500. A1CF antibody can be used for detection of A1CF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store A1CF antibody at -20 °C.
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- Antigène
- A1CF (APOBEC1 Complementation Factor (A1CF))
- Autre désignation
- A1CF (A1CF Produits)
- Synonymes
- anticorps ACF, anticorps ACF64, anticorps ACF65, anticorps APOBEC1CF, anticorps ASP, anticorps 1810073H04Rik, anticorps Acf, anticorps A1cft, anticorps Apobec-1, anticorps acf, anticorps acf64, anticorps acf65, anticorps apobec1cf, anticorps asp, anticorps A1CF, anticorps APOBEC1 complementation factor, anticorps apobec1 complementation factor, anticorps APOBEC1 complementation factor L homeolog, anticorps A1CF, anticorps A1cf, anticorps a1cf, anticorps a1cf.L
- Sujet
- Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
- Poids moléculaire
- 65 kDa
- ID gène
- 29974
- NCBI Accession
- NP_620311
- UniProt
- Q9NQ94
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