PPP4R2 antibody can be used for detection of PPP4R2 by ELISA at 1:62500. PPP4R2 antibody can be used for detection of PPP4R2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store PPP4R2 antibody at -20 °C.
anticorps PP4R2, anticorps BE691708, anticorps C230060M08Rik, anticorps ppp4r2, anticorps fe11b04, anticorps wu:fe11b04, anticorps ppp4r2-B, anticorps wu:fa17h08, anticorps wu:fc23g05, anticorps protein phosphatase 4 regulatory subunit 2, anticorps protein phosphatase 4, regulatory subunit 2, anticorps protein phosphatase 4, regulatory subunit 2a, anticorps protein phosphatase 4 regulatory subunit 2 S homeolog, anticorps protein phosphatase 4 regulatory subunit 2 L homeolog, anticorps protein phosphatase 4, regulatory subunit 2b, anticorps PPP4R2, anticorps Ppp4r2, anticorps ppp4r2a, anticorps ppp4r2.S, anticorps ppp4r2, anticorps ppp4r2.L, anticorps ppp4r2b
Sujet
PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.