Sep 15 anticorps

N° du produit ABIN2459187

Détail du produit anti-Sep 15 anticorps

Antigène: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sep 15 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human Septin 15.

Information d'application

Indications d'application: Septin 15 antibody can be used for detection of Septin 15 by ELISA at 1:312500. Septin 15 antibody can be used for detection of Septin 15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store Septin 15 antibody at -20 °C.

Détails sur Sep 15

Antigène: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Abstract: SEP15 Produits

Synonymes: anticorps 9430015P09Rik, anticorps cb29, anticorps zgc:86882, anticorps BcDNA:SD16138, anticorps Dmel\\CG7484, anticorps Prise 8, anticorps Sep15, anticorps selenoprotein F, anticorps CG7484 gene product from transcript CG7484-RB, anticorps SELENOF, anticorps Selenof, anticorps selenof, anticorps CG7484

Sujet: SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Poids moléculaire: 15 kDa

ID gène: 9403

NCBI Accession: NP_004252

UniProt: O60613