QPCT anticorps
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- Antigène Voir toutes QPCT Anticorps
- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp QPCT est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human QPCT.
- Top Product
- Discover our top product QPCT Anticorps primaire
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- Indications d'application
- QPCT antibody can be used for detection of QPCT by ELISA at 1:62500. QPCT antibody can be used for detection of QPCT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store QPCT antibody at -20 °C.
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- Antigène
- QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))
- Autre désignation
- QPCT (QPCT Produits)
- Synonymes
- anticorps GCT, anticorps QC, anticorps sQC, anticorps QPCT, anticorps 5730422A13Rik, anticorps Qpctl1, anticorps RGD1562284, anticorps qpct, anticorps glutaminyl-peptide cyclotransferase, anticorps glutaminyl-peptide cyclotransferase (glutaminyl cyclase), anticorps glutaminyl-peptide cyclotransferase L homeolog, anticorps QPCT, anticorps Qpct, anticorps M6_Spy0443, anticorps M5005_Spy_0416, anticorps M28_Spy0404, anticorps CJA_2408, anticorps CCNA_02733, anticorps Tsp_03182, anticorps qpct.L
- Sujet
- QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Poids moléculaire
- 38 kDa
- ID gène
- 25797
- NCBI Accession
- NP_036545
- UniProt
- Q16769
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