GLE1 anticorps
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- Antigène Voir toutes GLE1 Anticorps
- GLE1 (GLE1 RNA Export Mediator (GLE1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GLE1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GLE1.
- Top Product
- Discover our top product GLE1 Anticorps primaire
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- Indications d'application
- GLE1 antibody can be used for detection of GLE1 by ELISA at 1:1562500. GLE1 antibody can be used for detection of GLE1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store GLE1 antibody at -20 °C.
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- Antigène
- GLE1 (GLE1 RNA Export Mediator (GLE1))
- Autre désignation
- GLE1 (GLE1 Produits)
- Synonymes
- anticorps Dmel\\CG14749, anticorps GLE1, anticorps GLE1L, anticorps LCCS, anticorps LCCS1, anticorps hGLE1, anticorps Gle1l, anticorps 4933405K21Rik, anticorps AA553313, anticorps CG14749 gene product from transcript CG14749-RA, anticorps nucleoporin GLE1, anticorps RNA export factor Gle1, anticorps GLE1, RNA export mediator, anticorps GLE1 RNA export mediator, anticorps GLE1 RNA export mediator (yeast), anticorps CG14749, anticorps CpipJ_CPIJ014147, anticorps SJAG_03847, anticorps GLE1, anticorps Gle1
- Sujet
- GLE1 is a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 75 kDa
- ID gène
- 2733
- NCBI Accession
- NP_001490
- UniProt
- Q53GS7
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