SPO11
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
SPO11 antibody can be used for detection of SPO11 by ELISA at 1:1562500. SPO11 antibody can be used for detection of SPO11 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPO11 antibody at -20 °C.
Antigène
SPO11
(SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
anticorps CT35, anticorps SPATA43, anticorps TOPVIA, anticorps zgc:77876, anticorps AI449549, anticorps Meiotic recombination protein spo-11, anticorps SPO11, initiator of meiotic double stranded breaks, anticorps SPO11 meiotic protein covalently bound to DSB, anticorps spo-11, anticorps SPO11, anticorps Spo11, anticorps spo11
Sujet
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. SPO11 is similar in sequence and conserved features to the yeast meiotic recombination protein. It belongs to the TOP6A protein family. Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.