ATP6V1C1 anticorps

N° du produit ABIN2460074

Détail du produit anti-ATP6V1C1 anticorps

Antigène: ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V1C1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP6V1C1.

Information d'application

Indications d'application: ATP6V1C1 antibody can be used for detection of ATP6V1C1 by ELISA at 1:312500. ATP6V1C1 antibody can be used for detection of ATP6V1C1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP6V1C1 antibody at -20 °C.

Détails sur ATP6V1C1

Antigène: ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))

Autre désignation: ATP6V1C1 (ATP6V1C1 Produits)

Synonymes: anticorps ATP6C, anticorps ATP6D, anticorps VATC, anticorps Vma5, anticorps 1700025B18Rik, anticorps U13839, anticorps vatC, anticorps ATPase, anticorps atp6v1c1, anticorps si:zc215i13.2, anticorps wu:fd12h05, anticorps atp6v1c1l, anticorps zgc:92684, anticorps ATPase H+ transporting V1 subunit C1, anticorps ATPase, H+ transporting, lysosomal V1 subunit C1, anticorps ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1, anticorps ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 L homeolog, anticorps ATPase, H+ transporting, lysosomal, V1 subunit C1a, anticorps ATPase, H+ transporting, lysosomal, V1 subunit C1b, anticorps ATP6V1C1, anticorps Atp6v1c1, anticorps atp6v1c1, anticorps atp6v1c1.L, anticorps atp6v1c1a, anticorps atp6v1c1b

Sujet: ATP6V1C1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 42 kDa

ID gène: 528

NCBI Accession: NP_001686

UniProt: P21283

Pathways: Transition Metal Ion Homeostasis, Proton Transport