NFYA anticorps
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- Antigène Voir toutes NFYA Anticorps
- NFYA (Nuclear Transcription Factor Y, alpha (NFYA))
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Reactivité
- Humain, Souris, Rat, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFYA est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Antibody is supplied as total IgG.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFYA.
- Top Product
- Discover our top product NFYA Anticorps primaire
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- Indications d'application
- NFYA antibody can be used for detection of NFYA by ELISA at 1:312500. NFYA antibody can be used for detection of NFYA by western blot at 5.0-8.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 200 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFYA antibody at -20 °C.
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- Antigène
- NFYA (Nuclear Transcription Factor Y, alpha (NFYA))
- Autre désignation
- NFYA (NFYA Produits)
- Synonymes
- anticorps wu:fb16e03, anticorps ik:tdsubc_2b6, anticorps xx:tdsubc_2b6, anticorps NFYA, anticorps CBF-A, anticorps CBF-B, anticorps HAP2, anticorps NF-YA, anticorps AA407810, anticorps Cbf-b, anticorps SEZ-10, anticorps SEZ10, anticorps nuclear transcription factor Y, alpha, anticorps nuclear transcription factor Y subunit alpha, anticorps nuclear transcription factor-Y alpha, anticorps nfya, anticorps NFYA, anticorps Nfya
- Sujet
- NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
- Poids moléculaire
- 37 kDa, 34 kDa
- ID gène
- 4800
- NCBI Accession
- NP_002496
- UniProt
- P23511
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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