YAF2 anticorps
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- Antigène Voir toutes YAF2 Anticorps
- YAF2 (YY1 Associated Factor 2 (YAF2))
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Reactivité
- Humain, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp YAF2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YAF2.
- Top Product
- Discover our top product YAF2 Anticorps primaire
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- Indications d'application
- YAF2 antibody can be used for detection of YAF2 by ELISA at 1:62500. YAF2 antibody can be used for detection of YAF2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store YAF2 antibody at -20 °C.
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- Antigène
- YAF2 (YY1 Associated Factor 2 (YAF2))
- Autre désignation
- YAF2 (YAF2 Produits)
- Synonymes
- anticorps MGC75686, anticorps YAF2, anticorps zgc:136577, anticorps si:ch211-155a11.5, anticorps 2810021M11Rik, anticorps YY1 associated factor 2, anticorps YY1-associated factor 2, anticorps yaf2, anticorps YAF2, anticorps LOC100221270, anticorps Yaf2
- Sujet
- YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.
- Poids moléculaire
- 20 kDa
- ID gène
- 10138
- NCBI Accession
- NP_005739
- UniProt
- Q8IY57
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