CREB3
Reactivité: Humain, Chien, Porc
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
CREB3 antibody can be used for detection of CREB3 by ELISA at 1:312500. CREB3 antibody can be used for detection of CREB3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store CREB3 antibody at -20 °C.
Antigène
CREB3
(CAMP Responsive Element Binding Protein 3 (CREB3))
anticorps LUMAN, anticorps LZIP, anticorps AU044960, anticorps AW538053, anticorps C80076, anticorps LZIP-1, anticorps LZIP-2, anticorps Luman, anticorps creb3, anticorps luman, anticorps lzip, anticorps cAMP responsive element binding protein 3, anticorps cAMP responsive element binding protein 3 S homeolog, anticorps CREB3, anticorps Creb3, anticorps creb3.S
Sujet
CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.