MIER1 anticorps

N° du produit ABIN2460961

Détail du produit anti-MIER1 anticorps

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIER1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MIER1.

Information d'application

Indications d'application: MIER1 antibody can be used for detection of MIER1 by ELISA at 1:312500. MIER1 antibody can be used for detection of MIER1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MIER1 antibody at -20 °C.

Détails sur MIER1

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Autre désignation: MIER1 (MIER1 Produits)

Synonymes: anticorps 4933425I22Rik, anticorps 5830411K19Rik, anticorps mKIAA1610, anticorps mier1, anticorps wu:fb30a02, anticorps zgc:56179, anticorps mi-er1, anticorps ER1, anticorps MI-ER1, anticorps RGD1562337, anticorps MEIR1 treanscription regulator, anticorps MIER1 transcriptional regulator, anticorps mesoderm induction early response 1a, transcriptional regulator, anticorps mesoderm induction early response 1, transcriptional regulator L homeolog, anticorps Mier1, anticorps MIER1, anticorps mier1a, anticorps mier1.L

Sujet: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).

Poids moléculaire: 49 kDa

ID gène: 57708

NCBI Accession: NP_065999

UniProt: Q8NES5

Pathways: Chromatin Binding