KCNN1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
KCNN1 antibody can be used for detection of KCNN1 by ELISA at 1:312500. KCNN1 antibody can be used for detection of KCNN1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNN1 antibody at -20 °C.
Antigène
KCNN1
(Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 1 (KCNN1))
anticorps KCNN1, anticorps kcnn1, anticorps si:ch211-200a16.1, anticorps sk1, anticorps hsk1, anticorps skca1, anticorps MGC145919, anticorps KCa2.1, anticorps SK1, anticorps SKCA1, anticorps hSK1, anticorps AI854248, anticorps potassium calcium-activated channel subfamily N member 1, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b, anticorps potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1, anticorps small conductance calcium-activated potassium channel protein 1, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1, anticorps KCNN1, anticorps kcnn1b, anticorps kcnn1, anticorps LOC100456154, anticorps Kcnn1
Sujet
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.