PRDM12 anticorps

N° du produit ABIN2461913

Détail du produit anti-PRDM12 anticorps

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM12 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRDM12.

Information d'application

Indications d'application: PRDM12 antibody can be used for detection of PRDM12 by ELISA at 1:62500. PRDM12 antibody can be used for detection of PRDM12 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PRDM12 antibody at -20 °C.

Détails sur PRDM12

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Autre désignation: PRDM12 (PRDM12 Produits)

Synonymes: anticorps PRDM12, anticorps prdm12, anticorps MGC146714, anticorps PFM9, anticorps pfm9, anticorps Gm998, anticorps PR/SET domain 12, anticorps PR domain containing 12, anticorps PR domain containing 12 L homeolog, anticorps PR domain containing 12a, anticorps PRDM12, anticorps prdm12, anticorps prdm12.L, anticorps Prdm12, anticorps prdm12a

Sujet: PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.

Poids moléculaire: 40 kDa

ID gène: 59335

NCBI Accession: NP_067632

UniProt: Q9H4Q4