Coilin anticorps

N° du produit ABIN2463583

Détail du produit anti-Coilin anticorps

Antigène: Coilin (COIL)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coilin est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COIL.

Information d'application

Indications d'application: COIL antibody can be used for detection of COIL by ELISA at 1:312500. COIL antibody can be used for detection of COIL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COIL antibody at -20 °C.

Détails sur Coilin

Antigène: Coilin (COIL)

Autre désignation: COIL (COIL Produits)

Synonymes: anticorps p80c, anticorps coil, anticorps CG8710, anticorps Coilin, anticorps Dmel\\CG8710, anticorps LOC100218802, anticorps F3F19.5, anticorps F3F19_5, anticorps CLN80, anticorps p80-coilin, anticorps C79982, anticorps Cln80, anticorps p80, anticorps wu:fb08h11, anticorps sph1, anticorps Coilin, anticorps coilin, anticorps sphere organelles protein-like protein, anticorps coilin p80, anticorps coilin L homeolog, anticorps p80c, anticorps COIL, anticorps coil, anticorps AT1G13030, anticorps Coil, anticorps coil.L

Sujet: COIL is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies.The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 63 kDa

ID gène: 8161

NCBI Accession: NP_004636

UniProt: P38432

Pathways: Ribonucleoprotein Complex Subunit Organization