CIB1 anticorps (truncated)

N° du produit ABIN2464036

Détail du produit anti-CIB1 anticorps

Antigène: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Épitope: truncated

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CIB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: Ni-NTA purified truncated recombinant CIB1 expressed in E. Coli strain BL21 (DE3).

Clone: 5A1F5E12-5A1H7E12

Information d'application

Indications d'application: Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: CIB1 monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur CIB1

Antigène: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Autre désignation: CIB1 (CIB1 Produits)

Synonymes: anticorps zgc:112015, anticorps CIB, anticorps CIBP, anticorps KIP1, anticorps PRKDCIP, anticorps SIP2-28, anticorps Cibkip, anticorps Kip, anticorps Prkdcip, anticorps Cib, anticorps Sip2-28, anticorps calcium and integrin binding 1 (calmyrin), anticorps calcium and integrin-binding protein 1, anticorps calcium and integrin binding 1, anticorps Calcium and integrin-binding protein 1, anticorps cib1, anticorps CpipJ_CPIJ003501, anticorps CIB1, anticorps kip1, anticorps Cib1

Sujet: CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21 kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

ID gène: 10519

NCBI Accession: NP_001264693

UniProt: Q99828