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PDE9A anticorps (Internal Region)
PDE9A
Reactivité: Humain, Chien, Singe, Gibbon
IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2469457
Détail du produit anti-PDE9A anticorps
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Antigène
Voir toutes PDE9A Anticorps
PDE9A
(phosphodiesterase 9A (PDE9A))
Épitope
Tous les épitopes à travers PDE9A Anticorps.
Internal Region
Reactivité
Toutes les réactivités sur PDE9A Anticorps
Humain, Chien, Singe, Gibbon
Hôte
Toutes les hôtes sur PDE9A Anticorps
Lapin
Clonalité
Toutes les clonalités sur PDE9A Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PDE9A Anticorps
Cet anticorp PDE9A est non-conjugé
Application
Tous les applications à travers PDE9A Anticorps.
Immunohistochemistry (IHC)
Specificité
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purification
Immunoaffinity Chromatography
Immunogène
PDE9A antibody was raised against a peptide located near the internal domain of PDE9A (Human).
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Alternatives
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Information d'application
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Indications d'application
PDE9A antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
As with all antibodies avoid freeze/thaw cycles.
Stock
4 °C/-80 °C
Stockage commentaire
PDE9A antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Détails sur PDE9A
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Antigène
PDE9A
(phosphodiesterase 9A (PDE9A))
Autre désignation
PDE9A (PDE9A Produits )
Sujet
Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.
ID gène
5152
UniProt
O76083
Vus récemment
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