TLX1 anticorps (AA 300-330)
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- Antigène Voir toutes TLX1 Anticorps
- TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))
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Épitope
- AA 300-330
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Reactivité
- Souris, Humain, Rat, Boeuf (Vache), Chien, Lapin, Roussette (Chauve-souris), Singe, Poulet, Cheval, Hamster, Gibbon, Gorilla
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TLX1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Protein G Column
- Immunogène
- TLX1 antibody was raised against amino acids 300 - 330 of TLX1 (Human).
- Isotype
- IgG
- Top Product
- Discover our top product TLX1 Anticorps primaire
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- Indications d'application
- TLX1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, 0.2 % gelatin, 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies avoid freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- TLX1 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
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- Antigène
- TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))
- Autre désignation
- TLX1 (TLX1 Produits)
- Synonymes
- anticorps Hox-11, anticorps Hox11, anticorps HOX11, anticorps TCL3, anticorps XHox11, anticorps XHox11L2, anticorps hox11, anticorps tlx1-a, anticorps TLX-1, anticorps RGD1563655, anticorps SI:dZ46P4.1, anticorps Tlx-1, anticorps ztlx-1, anticorps T cell leukemia, homeobox 1, anticorps T-cell leukemia homeobox 1, anticorps T-cell leukemia homeobox 1 L homeolog, anticorps T-cell leukemia, homeobox 1, anticorps Tlx1, anticorps TLX1, anticorps tlx1.L, anticorps tlx1
- Sujet
- HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35,q24) or t(10:14)(q24,qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes. HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.
- ID gène
- 3195
- UniProt
- P31314
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