CDK2 anticorps
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- Antigène Voir toutes CDK2 Anticorps
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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Reactivité
- Humain, Souris, Xenopus laevis
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CDK2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
- Specificité
- Recognizes cdk2, Mr 33kD. Does not cross-react with other cdks.
- Purification
- Protein G Column
- Immunogène
- CDK2 monoclonal antibody was raised against recombinant CDK2 (Human).
- Isotype
- IgG
- Top Product
- Discover our top product CDK2 Anticorps primaire
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- Indications d'application
- CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies avoid freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store CDK2 antibody at 4 °C or -20 °C.
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- Antigène
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
- Autre désignation
- CDK2 (CDK2 Produits)
- Synonymes
- anticorps p33(CDK2), anticorps A630093N05Rik, anticorps wu:fa10c02, anticorps zgc:56598, anticorps zgc:77684, anticorps eg1, anticorps CDKN2, anticorps cdk2L, anticorps cyclin dependent kinase 2, anticorps cyclin-dependent kinase 2, anticorps cyclin-dependent kinase 2 S homeolog, anticorps CDK2, anticorps Cdk2, anticorps cdk2, anticorps cdk2.S
- Sujet
- Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.
- ID gène
- 1017
- UniProt
- P24941
- Pathways
- Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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