Endothelin anticorps (C-Term)

N° du produit ABIN2473437

Détail du produit anti-Endothelin anticorps

Antigène: Endothelin

Épitope: C-Term

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Endothelin est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoradiometric Assay (IRMA)

Specificité: Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.

Attributs du produit: Purified IgG

Purification: Purified

Immunogène: Synthetic peptide corresponding to the c-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA.

Clone: 3G10

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Références pour anticorps anti-Endothelin (ABIN2473437)

Yao, Morioka, Li, Oite: "Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion and activation in rat mesangial cells." dans: American journal of physiology. Renal physiology, Vol. 280, Issue 4, pp. F628-35, (2001) (PubMed).

Détails sur Endothelin

Antigène: Endothelin

Abstract: Endothelin Produits

ID gène: 1906, 1907, 1908

UniProt: P05305, P14138, P20800