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Piccolo anticorps (FITC)

PIC Reactivité: Souris WB, ELISA, ICC, IF Hôte: Souris Monoclonal 6H9-B6 FITC
N° du produit ABIN2482382
  • Antigène Tous les produits Piccolo (PIC)
    Piccolo (PIC)
    Reactivité
    • 24
    • 15
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 20
    • 13
    • 1
    • 1
    Souris
    Clonalité
    • 22
    • 13
    Monoclonal
    Conjugué
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Piccolo est conjugé à/à la FITC
    Application
    • 30
    • 16
    • 15
    • 11
    • 9
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects ~550 kDa. No cross-reactivity to Bassoon.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Full length recombinant protein (GenBank ID: BC001304.1)
    Clone
    6H9-B6
    Isotype
    IgG2b kappa
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2482382 was sufficient for detection of Piccolo in 20 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    Piccolo (PIC)
    Autre désignation
    Piccolo (PIC Produits)
    Sujet
    Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains (1, 2). In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) (3). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 (2).
    ID gène
    26875
    NCBI Accession
    NP_001104266
    UniProt
    Q9QYX7
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