NALCN anticorps (AA 1659-1738) (Atto 390)
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- Antigène Voir toutes NALCN Anticorps
- NALCN (Sodium Leak Channel, Non-Selective (NALCN))
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Épitope
- AA 1659-1738
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Reactivité
- Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NALCN est conjugé à/à la Atto 390
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- Detects ~200 kDa.
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Protein G Purified
- Immunogène
- Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
- Clone
- S187-7
- Isotype
- IgG1
- Top Product
- Discover our top product NALCN Anticorps primaire
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- Indications d'application
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Commentaires
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1 μg/ml of ABIN2483019 was sufficient for detection of NALCN in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- Antigène
- NALCN (Sodium Leak Channel, Non-Selective (NALCN))
- Autre désignation
- NALCN (NALCN Produits)
- Synonymes
- anticorps VGCNL1, anticorps zgc:113349, anticorps CanIon, anticorps bA430M15.1, anticorps A530023G15Rik, anticorps AI849508, anticorps Vgcnl1, anticorps sodium leak channel, non-selective, anticorps NALCN, anticorps nalcn, anticorps Nalcn
- Sujet
- NALCN (sodium leak channel non-selective protein), alsoknown as CanIon or VGCNL1 (voltage gated channel-like protein 1), is a 1738 amino acid multi-pass membrane protein that belongs to the cation-nonselective channel family. NALCN is highly conserved in mammals and is widely expressed in the central nervous system. Activated by NK-1R, NALCN is a voltage-independent, nonselective cation channel which is permeable to sodium, potassium and calcium ions. NALCN is responsible for background sodium ion leak conductance in neurons and regulates basal excitability of the nervous systems. Defects of NALCN in mice causes disruption in respiratory rhythm and death occurs within 24 hours of birth. Three isoforms of NALCN exists due to alternative splicing events.
- ID gène
- 266760
- NCBI Accession
- NP_705894
- UniProt
- Q6Q760
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