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NALCN anticorps (AA 1659-1738) (Atto 488)

NALCN Reactivité: Rat WB, ICC, IF Hôte: Souris Monoclonal S187-7 Atto 488
N° du produit ABIN2483020
  • Antigène Voir toutes NALCN Anticorps
    NALCN (Sodium Leak Channel, Non-Selective (NALCN))
    Épitope
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 1659-1738
    Reactivité
    • 14
    • 6
    • 3
    • 1
    Rat
    Hôte
    • 14
    • 6
    Souris
    Clonalité
    • 14
    • 6
    Monoclonal
    Conjugué
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NALCN est conjugé à/à la Atto 488
    Application
    • 15
    • 11
    • 11
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects ~200 kDa.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
    Clone
    S187-7
    Isotype
    IgG1
    Top Product
    Discover our top product NALCN Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2483020 was sufficient for detection of NALCN in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    NALCN (Sodium Leak Channel, Non-Selective (NALCN))
    Autre désignation
    NALCN (NALCN Produits)
    Synonymes
    anticorps VGCNL1, anticorps zgc:113349, anticorps CanIon, anticorps bA430M15.1, anticorps A530023G15Rik, anticorps AI849508, anticorps Vgcnl1, anticorps sodium leak channel, non-selective, anticorps NALCN, anticorps nalcn, anticorps Nalcn
    Sujet
    NALCN (sodium leak channel non-selective protein), alsoknown as CanIon or VGCNL1 (voltage gated channel-like protein 1), is a 1738 amino acid multi-pass membrane protein that belongs to the cation-nonselective channel family. NALCN is highly conserved in mammals and is widely expressed in the central nervous system. Activated by NK-1R, NALCN is a voltage-independent, nonselective cation channel which is permeable to sodium, potassium and calcium ions. NALCN is responsible for background sodium ion leak conductance in neurons and regulates basal excitability of the nervous systems. Defects of NALCN in mice causes disruption in respiratory rhythm and death occurs within 24 hours of birth. Three isoforms of NALCN exists due to alternative splicing events.
    ID gène
    266760
    NCBI Accession
    NP_705894
    UniProt
    Q6Q760
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