LRP4 anticorps (AA 26-350) (Biotin)

N° du produit ABIN2483386

Détail du produit anti-LRP4 anticorps (Biotin)

Antigène: LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))

Épitope: AA 26-350

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LRP4 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: Detects the extracellular domain of LRP4 ~215 kDa. Degradation product can be seen at ~150 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4

Clone: S207-27

Isotype: IgG2a

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN2483386 was sufficient for detection of LRP4 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur LRP4

Antigène: LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))

Autre désignation: LRP4 (LRP4 Produits)

Synonymes: anticorps CLSS, anticorps LRP-4, anticorps LRP10, anticorps MEGF7, anticorps SOST2, anticorps Megf7, anticorps 6430526J12Rik, anticorps D230026E03, anticorps mdig, anticorps LRP4, anticorps lrp10, anticorps megf7, anticorps LDL receptor related protein 4, anticorps low density lipoprotein receptor-related protein 4, anticorps LRP4, anticorps Lrp4, anticorps lrp4

Sujet: Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.

ID gène: 83469

NCBI Accession: NP_766256

UniProt: Q8VI56

Pathways: Skeletal Muscle Fiber Development