SLC17A7 anticorps (AA 493-560) (Atto 390)
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- Antigène Voir toutes SLC17A7 Anticorps
- SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))
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Épitope
- AA 493-560
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Reactivité
- Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SLC17A7 est conjugé à/à la Atto 390
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- Detects ~52 kDa. No cross-reactivity against VGlut2.
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Protein G Purified
- Immunogène
- Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1
- Clone
- S28-9
- Isotype
- IgG1
- Top Product
- Discover our top product SLC17A7 Anticorps primaire
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- Indications d'application
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- Commentaires
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1 μg/ml of ABIN2483716 was sufficient for detection of VGLut1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- Antigène
- SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))
- Autre désignation
- VGLUT1 (SLC17A7 Produits)
- Synonymes
- anticorps 2900052E22Rik, anticorps AI851913, anticorps VGluT1, anticorps Vglut1, anticorps BNPI, anticorps VGLUT1, anticorps slc17a7, anticorps vglut1, anticorps solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, anticorps solute carrier family 17 member 7, anticorps solute carrier family 17 (vesicular glutamate transporter), member 7a, anticorps Slc17a7, anticorps SLC17A7, anticorps slc17a7a
- Sujet
- VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).
- ID gène
- 116638
- NCBI Accession
- NP_446311
- UniProt
- Q62634
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