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MDC1 anticorps (N-Term) (PE)

MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 PE
N° du produit ABIN2484156
  • Antigène Voir toutes MDC1 Anticorps
    MDC1 (Mdc1 (MDC1))
    Épitope
    • 21
    • 17
    • 15
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 60
    • 53
    • 16
    • 12
    • 11
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 50
    • 36
    Souris
    Clonalité
    • 50
    • 36
    Monoclonal
    Conjugué
    • 30
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MDC1 est conjugé à/à la PE
    Application
    • 66
    • 30
    • 14
    • 13
    • 13
    • 12
    • 12
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
     Réactivité croisée
    Chimpanzé, Boeuf (Vache), Humain, Souris
    Purification
    Protein G Purified
    Immunogène
    GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
    Clone
    P2B11
    Isotype
    IgG1
    Top Product
    Discover our top product MDC1 Anticorps primaire
  • Indications d'application
    • WB (1:2000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    0.5 μg/ml of ABIN2484156 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    MDC1 (Mdc1 (MDC1))
    Autre désignation
    MDC1 (MDC1 Produits)
    Synonymes
    anticorps 6820401C03, anticorps AA413496, anticorps Nfbd1, anticorps mKIAA0170, anticorps NFBD1, anticorps mediator of DNA damage checkpoint 1, anticorps mediator of DNA-damage checkpoint 1, anticorps Mdc1, anticorps MDC1
    Sujet
    MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
    ID gène
    240087
    NCBI Accession
    NP_001010833
    UniProt
    Q5PSV9
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